Filagra Oral Jelly can interact with certain medications, including other PDE5 inhibitors, alpha-blockers, and drugs containing nitrates. It's important to inform your healthcare provider about all medications you are taking, including prescription medications, over-the-counter drugs, and supplements. Individuals with certain medical conditions, such as cardiovascular disease, liver or kidney impairment, or a history of stroke, should use Filagra Oral Jelly with caution and under the guidance of a healthcare provider. It's also important to avoid using Filagra Oral Jelly with nitrates or alpha-blockers, as this can lead to a dangerous drop in blood pressure.